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Description:
Type 1 diabetes is caused by selective T-cell-mediated destruction of pancreatic beta cells. GAD antibodies (GADA) are more common in Type 1 diabetic subjects diagnosed at an older age, whereas insulinoma-antigen 2 antibodies (IA-2A) are more common in subjects with younger onset. Islet autoantibodies are the main markers of pancreatic autoimmunity in Type 1 diabetes (T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA), protein phosphatase-like IA-2 (IA-2A), and ZnT8 (ZnT8A), all antigens that are found on secretory granules within pancreatic beta cells.
Product Details:
Code |
Parameter |
Test/kit |
Platform |
C89049G |
IA-2A |
2×50 Tests |
CLIA |
C89048G |
IAA |
2×50 Tests |
CLIA |
C89047G |
GADA |
2×50 Tests |
CLIA |
C89050G |
ICA |
2×50 Tests |
CLIA |
C89051G |
ZnT8A |
2×50 Tests |
CLIA |
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